• The Human Upgrade with Dave Asprey

  • By: Dave Asprey
  • Podcast

The Human Upgrade with Dave Asprey

By: Dave Asprey
  • Summary

  • For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.

    You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.

    Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.

    Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life.

    © Copyright © Bulletproof Media 2023
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Episodes
  • What You DON'T Know About Women’s Health! From Microbiome to Major Impact with Priyanka Jain : 1227
    Nov 28 2024
    Is this the missing link in fertility? The vaginal microbiome could be the most overlooked factor in optimizing women’s health, from fertility and hormonal balance to preventing infections and improving quality of life. In this groundbreaking episode, Dave Asprey talks to Priyanka Jain, co-founder and CEO of Evvy, about how understanding and improving the vaginal microbiome can transform women’s health outcomes. Priyanka shares how Evvy is advancing women’s health through cutting-edge genomic research and AI-powered insights, offering solutions to challenges like bacterial vaginosis, yeast infections, recurrent UTIs, and even infertility. You’ll learn why this critical microbiome plays such a vital role, how hormonal changes and lifestyle impact it, and how personalized approaches can improve reproductive and overall health. This episode explores not just women’s health but also how understanding the vaginal microbiome can influence relationships, biohacking, and even groundbreaking fertility research. Don’t miss this deep dive into the science and solutions shaping the future of health. Here’s what you’ll learn in this episode:  • The critical role the vaginal microbiome plays in women’s health and fertility  • How hormonal changes affect vaginal health and microbiome balance  • The link between vaginal microbiome imbalances and conditions like bacterial vaginosis, yeast infections, and UTIs  • Evvy’s innovative approach to using AI and genomics for personalized health insights  • Practical tips for maintaining microbiome health, including probiotics, hydration, and hormone balance  • The connection between the vaginal microbiome and overall quality of life Resources:  • 2025 Biohacking Conference – https://biohackingconference.com/2025  • Shop at Evvy (Use coupon code DAVE for $10 off!) – https://shareasale.com/r.cfm?b=1862577&u=2810239&m=116251&urllink=&afftrack= (Use coupon code DAVE for $10 off!)  • Follow Evvy on Instagram – https://www.instagram.com/evvy  • Danger Coffee – https://dangercoffee.com  • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/  • Dave Asprey’s Website – https://daveasprey.com  • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books  • Dave Asprey’s Linktree – https://linktr.ee/daveasprey  • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com  • Own an Upgrade Labs – https://ownanupgradelabs.com  • Upgrade Labs – https://upgradelabs.com  • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Sponsors: - Calroy | Head to https://calroy.com/dave for an exclusive discount. Timestamps:  • 00:00 Trailer  • 00:35 Introduction to Vaginal Microbiome  • 01:12 Meet Priyanka Jain of Evvy  • 02:03 Understanding the Vaginal Microbiome  • 04:37 Challenges in Women’s Health  • 09:55 Impact of Lifestyle on Vaginal Health  • 11:22 The Role of Diet and Supplements  • 15:24 Sexual Health and Vaginal Microbiome  • 27:25 Menopause and Vaginal Health  • 31:23 Optimizing Vaginal Health  • 39:31 Exploring Women’s Health Data  • 41:17 The Role of Vaginal Microbiome in Fertility  • 43:44 Affordable Testing and Discount Offers  • 45:31 The Impact of Lubricants on Vaginal Health  • 46:20 Innovative Ideas for Probiotic Products  • 47:29 Audience Questions and Precision Medicine  • 48:04 The Importance of Data in Women’s Health  • 54:31 Marketing and Misinformation in Vaginal Health  • 01:06:34 The Connection Between Diet and Vaginal Health  • 01:12:49 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    1 hr and 12 mins
  • The World’s BEST Alcohol Alternative. Pleasure, Relaxation, and Clarity with TRU KAVA : 1226
    Nov 26 2024
    Is alcohol losing its grip as the go-to social drink? Enter kava—a centuries-old Polynesian plant that’s gaining global recognition for its ability to relax the mind, elevate mood, and enhance social connection without the toxic effects of alcohol. Kava, particularly in the form of TRU KAVA, is a psychoactive yet non-intoxicating drink that offers the perfect balance of calm focus and mental clarity. In this episode, Dave Asprey welcomes Cameron George, founder of TRU KAVA, to discuss why kava is becoming the drink of choice for those seeking a healthier, more connected lifestyle. Learn how kava impacts neurotransmitters like GABA and dopamine, enhances creativity and emotional grounding, and even helps the body recover from stress and trauma. Discover why kava is taking center stage in the biohacking and sober-curious movements as a new tool for wellness and connection. Here’s what you’ll learn in this episode: • Why 41% of Americans and 61% of Gen Z are drinking less alcohol • What kava is, how it works, and its history as a ceremonial and social beverage • The science behind kava’s calming and neuroprotective effects • How kava supports creativity, emotional resilience, and authentic social connection • Practical uses for kava, including stress relief, sleep enhancement, and travel recovery Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • TRU KAVA – https://www.trukava.com • TRU KAVA Instagram – https://www.instagram.com/trukava • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Sponsors: -Quantum Upgrade |Go to https://quantumupgrade.io/Dave for a free trial. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Timestamps: • 00:00 Intro • 00:37 Introduction to Alcohol Trends • 01:57 Meet Cameron George and TRU KAVA • 02:29 What is Kava? • 05:03 Kava’s Effects on the Brain • 06:53 Kava vs. Alcohol • 08:54 Active Compounds in Kava • 10:10 Kava’s Safety and Standardization • 16:17 Kava in Social Settings • 21:28 Kava and Psychedelics • 31:26 Kava for Public Speaking and Anxiety • 34:04 Kava in the Workplace: Enhancing Team Creativity • 35:22 Kava and Libido: The Unexpected Benefits • 36:06 Biohacking with Kava: Energy Allocation and Community • 39:00 Kava’s Role in Meditation and Emotional Awareness • 42:04 Kava During Pregnancy: Safety and Traditions • 44:37 Kava’s Neuroprotective Properties: A Deep Dive • 45:49 Kava and EMF Sensitivity: A Surprising Connection • 48:39 Kava for Frequent Travelers: Enhancing Mitochondrial Health • 52:46 Kava and Metabolic Health: Fasting and Fat Burning • 57:14 Kava Products: Oils, Beverages, and Their Uses • 01:01:27 The Future of Kava: Social Impact and Cultural Integration • 01:05:28 Conclusion: The Potential of Kava in Modern Society See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    1 hr and 7 mins
  • Urolithin A’s Secret to YOUTHFUL ENERGY and the Fight Against Inflammaging : 1225
    Nov 22 2024
    Have we finally discovered the key to youthful energy, longevity, and cellular health? In this episode, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert on mitochondrial health, cellular regeneration, and anti-aging science. With over 20 years of research, 50 clinical trials, and 15 patents under his belt, Dr. Singh unpacks the groundbreaking science behind Urolithin A, a revolutionary postbiotic that boosts mitochondrial function, enhances immune system resilience, and combats chronic inflammation. This episode goes beyond cutting-edge science. Dr. Singh reveals practical, real-world strategies to combat “inflammaging”—the chronic, low-grade inflammation that accelerates aging. Learn how fasting, gut health, and mitochondrial boosters like Urolithin A can rejuvenate your cells, fight fatigue, and supercharge your energy, vitality, and longevity. Here’s what you’ll learn in this episode: • What Urolithin A is and its role in mitochondrial health and cellular energy production • How to reverse “inflammaging” and reduce inflammation through nutrition, fasting, and biohacking • The connection between mitochondrial dysfunction and immune system aging • Real-life benefits of Urolithin A for energy levels, athletic recovery, skin health, and longevity • Why mitochondrial support is critical for combating aging and improving overall performance Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Timeline Nutrition - https://www.timeline.com/dave to get 10% off your first order • Timeline Instagram – https://www.instagram.com/timeline_longevity/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps: • 00:00 Introduction to Longevity and Mitochondria • 01:28 The Role of Mitochondria in Immune Health • 03:36 Understanding Inflammaging and Immune Aging • 07:47 Measuring Immune Health and Inflammation • 13:33 Urolithin A: A Mitochondrial Booster • 16:46 Dosage and Effects of Urolithin A • 26:11 Urolithin A and Exercise Performance • 28:31 Urolithin A for Skin Health • 31:34 Collagen and Aging: The Role of MMPs • 33:27 Personal Experience with MMPs and Recovery • 35:04 Measuring MMPs and Their Impact on Longevity • 36:18 Skin Health and Urolithin A • 38:39 Exploring Urolithin A’s Broader Benefits • 40:33 Brain Health and Urolithin A • 43:33 Combining Supplements for Optimal Health • 45:54 Omega-3s and Mitochondrial Health • 46:51 Ketones, MCTs, and Urolithin A • 54:30 Final Thoughts on MitoPure and Supplementation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    59 mins

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