• Clinical Highlights: Oral SERDs for Patients With HR+/HER2- ESR1-Mutated Advanced Breast Cancer

  • Jan 9 2025
  • Length: 36 mins
  • Podcast

Clinical Highlights: Oral SERDs for Patients With HR+/HER2- ESR1-Mutated Advanced Breast Cancer

  • Summary

  • In this episode, listen to Virginia Kaklamani, MD, DSc; Erica L. Mayer, MD, MPH; and Laura M. Spring, MD, share their clinical insights and takeaways from a live symposium, including from key abstracts presented at the 2024 San Antonio Breast Cancer Symposium:

    • Estrogen receptor mutations in patients With HR-positive/HER2-negative advanced breast cancer
    • Current guideline recommendations for when to pursue ESR1 mutation testing mutations in patients with HR-positive/HER2-negative advanced breast cancer
    • Choice and sequencing of next line of systemic therapy for ESR1-mutated advanced breast cancer based on tumor molecular alterations
    • Overview of class-related and unique adverse events with approved and emerging oral SERDS
    • Expert recommendations for the management of oral SERDs-related adverse events

    Program faculty:

    Virginia Kaklamani, MD, DSc
    Professor of Medicine
    Ruth McLean Bowman Bowers Chair in Breast Cancer Research and Treatment
    A.B. Alexander Distinguished Chair in Oncology
    Leader
    Breast Oncology Program
    UT Health San Antonio
    MD Anderson Cancer Center
    San Antonio, Texas

    Erica L. Mayer, MD, MPH
    Director of Breast Cancer Clinical Research
    Dana-Farber Cancer Institute
    Associate Professor in Medicine
    Harvard Medical School
    Boston, Massachusetts

    Laura M. Spring, MD
    Breast Medical Oncologist
    Mass General Hospital Cancer Center
    Harvard Medical School
    Boston, Massachusetts

    Resources:
    To download the slides associated with this podcast discussion, please visit the program page.

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