Biology Genetics

Nessa Carey’s The Epigenetics Revolution looks at how modern biology is rewriting our understanding of genetics, disease and inheritance....

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

Humans are a puzzling species. On the one hand, we struggle to survive on our own in the wild, often failing to overcome even basic challenges, like obtaining food, building shelters, or avoiding predators. On the other hand, human groups have produced ingenious technologies, sophisticated languages, and complex institutions that have permitted us to successfully expand into a vast range of diverse environments. What has enabled us to dominate the globe, more than any other species, while remaining virtually helpless as lone individuals?

In Survival of the Prettiest, Nancy Etcoff, a faculty member at Harvard Medical School and a practicing psychologist at Massachusetts General Hospital, argues that beauty is neither a cultural construction, an invention of the fashion industry, nor a backlash against feminism - it's in our biology.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

Australopithecines, dinosaurs, trilobites - such fossils conjure up images of lost worlds filled with vanished organisms. But in the full history of life, ancient animals, even the trilobites, form only the half-billion-year tip of a nearly four-billion-year iceberg. Andrew Knoll explores the deep history of life from its origins on a young planet to the incredible Cambrian explosion, presenting a compelling new explanation for the emergence of biological novelty.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

Naming Darwin's Black Box to the National Review's list of the 100 most important nonfiction works of the 20th century, George Gilder wrote that it "overthrows Darwin at the end of the 20th century in the same way that quantum theory overthrew Newton at the beginning". Discussing the book in the New Yorker in May 2005, H. Allen Orr said of Behe, "He is the most prominent of the small circle of scientists working on intelligent design, and his arguments are by far the best known."

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry.

At once a spirited defense of Darwinian explanations of biology and an elegant primer on evolution for the general listener, What Evolution Is poses the questions at the heart of evolutionary theory and considers how our improved understanding of evolution has affected the viewpoints and values of modern man.

Scientists' understanding of life is progressing more rapidly than at any point in human history, from the extraordinary decoding of DNA to the controversial emergence of biotechnology. Featuring pioneering biologists, geneticists, physicists, and science writers, Life explains just how far we've come - and takes a brilliantly educated guess at where we're heading.

She Has Her Mother’s Laugh presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities....

Breathtaking, brilliant and passionate, these essays, journalism, lectures and letters make an unanswerable case for the wonder of scientific discovery and its power to stir the imagination; for the practical necessity of scientific endeavour to society; and for the importance of the scientific way of thinking – particularly in today’s ‘post-truth’ world.

Sentient assembles a menagerie of zoological creatures - from land, air, sea and all four corners of the globe - to understand what it means to be human. Through their eyes, ears, skins, tongues and noses, the furred, finned and feathered reveal how we sense and make sense of the world, as well as the untold scientific revolution stirring in the field of human perception.

When Charles Darwin finished The Origin of Species, he thought that he had explained every clue but one. Though his theory could explain many facts, Darwin knew that there was a significant event in the history of life that his theory did not explain. During this event, the "Cambrian explosion", many animals suddenly appeared in the fossil record without apparent ancestors in earlier layers of rock. In Darwin's Doubt, Stephen C. Meyer tells the story of the mystery surrounding this explosion of animal life.

The scientist who has been dubbed the “Father of Intelligent Design” and author of the groundbreaking book Darwin’s Black Box contends that recent scientific discoveries further disprove Darwinism and strengthen the case for an intelligent creator.

The Ancestor's Tale is a pilgrimage back through time - a journey on which we meet up with fellow pilgrims as we and they converge on our common ancestors. Chimpanzees join us at about six million years in the past, gorillas at seven million years, orangutans at 14 million years, as we stride on together, a growing band. The journey provides the setting for a collection of some 40 tales.

We human beings share 98 percent of our genes with chimpanzees. Yet humans are the dominant species on the planet - having founded civilizations and religions, developed intricate and diverse forms of communication, learned science, built cities, and created breathtaking works of art - while chimps remain animals concerned primarily with the basic necessities of survival. What is it about that two percent difference in DNA that has created such a divergence between evolutionary cousins?