Genetic History

An almost limitless archive of our history lies hidden inside our bodies, and this book traces the ancient story of Scotland from that scientific viewpoint. The mushrooming of genetic studies, of DNA analysis, is rewriting history in spectacular fashion. In Scotland: A Genetic Journey, Alistair Moffat explores the history that is printed on our genes, and in a remarkable new approach, uncovers the detail of where Scots are from, where they have journeyed, and who they are - and in so doing, vividly colors in a DNA map of Scotland.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

What is human consciousness, and how is it possible? This question fascinates thinking people from poets and painters to physicists, psychologists, and philosophers. From Bacteria to Bach and Back is Daniel C. Dennett's brilliant answer, extending perspectives from his earlier work in surprising directions, exploring the deep interactions of evolution, brains, and human culture.

Best-selling author Brian Fagan brings early humans out of the deep freeze with his trademark mix of erudition, cutting-edge science, and vivid storytelling. Cro-Magnon reveals human society in its infancy, facing enormous environmental challenges - including a rival species of humans, the Neanderthals. For ten millennia, Cro-Magnons lived side by side with Neanderthals, an encounter that Fagan fills with drama.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. 

Naming Darwin's Black Box to the National Review's list of the 100 most important nonfiction works of the 20th century, George Gilder wrote that it "overthrows Darwin at the end of the 20th century in the same way that quantum theory overthrew Newton at the beginning". Discussing the book in the New Yorker in May 2005, H. Allen Orr said of Behe, "He is the most prominent of the small circle of scientists working on intelligent design, and his arguments are by far the best known."

Exogenesis: Hybrid Humans offers a deep dive into the strongest ever scientific evidence that supports the popular belief that Earth has been visited in prehistory, but goes even further, concluding that there is also compelling evidence of alien involvement with the human genome. The broader history of possible extraterrestrial contact is explored alongside a look at current events in the subject of alien disclosure with the result of highlighting evidence of a contact continuum that has continued since the dawn of humanity.

Resistance to malaria. Blue eyes. Lactose tolerance. What do all of these traits have in common? Every one of them has emerged in the last 10,000 years.

Here is the extraordinary story of the unfolding of life on Earth, told by Michael J. Benton, a world-renowned authority on biodiversity. Ranging over four billion years, Benton weaves together the latest findings on fossils, earth history, evolutionary biology, and many other fields to highlight the great leaps that enabled life to evolve from microbe to human - big breakthroughs that made whole new ways of life possible - including cell division and multicellularity, hard skeletons, the move to land, the origin of forests, the move to the air.

In his provocative new book, evolutionary biologist Jerry A. Coyne lays out in clear, dispassionate detail why the toolkit of science, based on reason and empirical study, is reliable, while that of religion - including faith, dogma, and revelation - leads to incorrect, untestable, or conflicting conclusions.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

Among the estimated 100 billion solar systems in the known universe, evolving life is surely abundant. That evolution is a process of "becoming" in each case. Since Newton, we have turned to physics to assess reality. But physics alone cannot tell us where we came from, how we arrived, and why our world has evolved past the point of unicellular organisms to an extremely complex biosphere.

How four tools enabled humanity to control its destiny What enabled us to go from simple stone tools to smartphones? How did bands of hunter-gatherers evolve into multinational empires? Listeners of Sapiens will say a cognitive revolution - a dramatic evolutionary change that altered our brains, turning primitive humans into modern ones - caused a cultural explosion. In Transcendence, Gaia Vince argues instead that modern humans are the product of a nuanced coevolution of our genes, environment, and culture that goes back into deep time.

In Monarchs and Milkweed, Anurag Agrawal presents a vivid investigation into how the monarch butterfly has evolved closely alongside the milkweed - a toxic plant named for the sticky white substance emitted when its leaves are damaged - and how this inextricable and intimate relationship has been like an arms race over the millennia, a battle of exploitation and defense between two fascinating species.

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

Tucked away in Siberia, there are furry, four-legged creatures with wagging tails and floppy ears that are as docile and friendly as any lapdog. But, despite appearances, these are not dogs - they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken - imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time.

DNA Demystified satisfies the public appetite for and curiosity about DNA and genetics. The book begins with the basic groundwork and a brief history of DNA and genetics. Chapters then cover newsworthy topics, including DNA fingerprinting, using DNA in forensic analyses, and identifying cold-case criminals. For listeners intrigued by the proliferation of at-home DNA tests, the text includes fascinating explorations of genetic genealogy and family tree construction.

From star-nosed moles that have super-sensing snouts to electric eels that paralyze their prey, animals possess unique and extraordinary abilities. In Great Adaptations, Kenneth Catania presents an entertaining and engaging look at some of nature's most remarkable creatures. Telling the story of his biological detective work, Catania sheds light on the mysteries behind the behaviors of tentacled snakes, tiny shrews, zombie-making wasps, and more. 

This is a story about you. It is the history of who you are and how you came to be. It is unique to you, as it is for every one of the 100 billion modern humans who has ever drawn breath. But it is also our collective story, because in each of our genomes we carry the history of the whole of our species.