In Episode 41 of the Pound of Cure Weight Loss podcast, we explore the growing use of GLP-1 medications for weight loss, particularly focusing on compounded versions of Semaglutide and Tirzepatide. These medications, typically found in Ozempic, Wegovy, Zepbound, and Mounjaro, have become incredibly popular for their effectiveness in helping patients lose weight. With shortages of these factory-produced drugs, compounding pharmacies have emerged as a more accessible and affordable alternative for many. But what exactly does compounding mean, and is it safe?

We break down how compounding pharmacies create custom versions of medications, often offering a lower-cost option. While the appeal is strong, compounded meds come with potential risks. Quality and dosage can vary significantly, raising concerns about safety and effectiveness. We share patient stories and real-world examples of how compounded versions can differ from the original medications in potency and results, and we explain why patients should approach compounded GLP-1 meds with caution.

Beyond the legal and safety considerations, we also discuss practical tips for those taking GLP-1 medications for weight loss, such as staying hydrated. These meds not only curb hunger but also reduce the body’s natural thirst response, making it easy to become dehydrated. We offer simple strategies for maintaining hydration while on these medications, which is crucial for overall health and well-being.

Finally, we look ahead to the future of compounded medications. As shortages ease and patents become enforceable, compounded versions of GLP-1 drugs may become less common. We also touch on the possibility of generic versions hitting the market, making these life-changing medications more affordable and accessible. If you're considering compounded meds or just want to learn more about your options, this episode offers valuable insights into how to make the best choices for your weight loss journey.

In this episode, we cover a wide range of topics related to diabetes, weight loss, and bariatric surgery. We kick things off by talking about the underlying cause of diabetes. Most people believe that diabetes is caused by an over consumption of carbohydrates. But that’s incorrect. In fact, studies show that the consumption of animal fat is what causes your insulin receptors to become less sensitive.

Next, we answer the question, “How long should you be on the Metabolic Reset Diet?” It’s a question we get asked daily and, as usual, the answer isn’t universal. Rather, it’s about determining what things you need to change in order to make the Metabolic Reset Diet work for you long-term. We offer practical advice on how to do this.

Next, we tackle weight regain after bariatric surgery, especially for those who’ve had a sleeve gastrectomy (VSG). Almost half of patients deal with weight regain, and it’s not just about eating too much or slacking on exercise. The conversation dives into why this happens, focusing on hormonal changes and the body's natural resistance to weight loss. We also talk about how combining surgery with medications like GLP-1s can help manage weight over the long term.

Finally, we share some tips on how to minimize hair loss after bariatric surgery. It’s a common concern for most patients. We cover practical ways to reduce hair thinning, including preventative measures like proper nutrition, key supplements, and medication to build reserves that assist in keeping as much of your hair as possible after surgery.

In this episode, Laura, a previous guest on the podcast, returns to share more about her successful peer support group for those who have undergone weight loss surgery. The conversation revolves around the value of community and how it provides a sense of connection and understanding for people on their weight loss journeys. Laura's group, lovingly nicknamed "Laura's Losers," meets regularly to offer emotional support, share personal stories, and discuss tips for staying on track.

Laura emphasizes the importance of creating a welcoming, living-room-style atmosphere where participants can openly discuss their struggles, especially around topics like post-op stalls and feeling isolated. She shares her own experiences, including her recent vacation where she was able to indulge mindfully while still staying true to her health goals. This helps alleviate some of the common fears that new patients have about life after surgery.

The conversation touches on the emotional toll of weight loss, particularly the societal pressure and feelings of guilt that many people face. Laura, along with the hosts, stress the importance of self-compassion and avoiding the trap of perfectionism. They remind listeners that there is no "finish line" when it comes to health, and that setbacks are a normal part of the journey.

The episode ends with a discussion of future plans for the group, including in-person meetups and continued support, underscoring the ongoing importance of community in long-term weight loss success.