• #427 Longevity Scientist Shares What Affects Biological Age and How to Slow Aging - Raghav Sehgal
    Nov 15 2024

    Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

    Timestamps:

    • 00:00 Intro
    • 00:35 Raghav’s new study on epigenetic age
    • 04:25 Biological age explained
    • 10:45 How epigenetics affects aging
    • 12:40 Biological age clocks and biomarkers
    • 21:50 Top performers in lowering epigenetic age
    • 32:20 How chronological age affects biological age
    • 35:20 Gene therapies
    • 40:10 Effect of diet and exercise
    • 45:40 What biomarkers affect biological age
    • 49:45 Organ aging
    • 58:00 Final thoughts


    Raghav Sehgal Twitter: https://twitter.com/rv_sehgal

    Raghav Sehgal website: https://www.raghav-sehgal.com/

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    1 hr and 6 mins
  • #426 The Truth About Peptides for Regeneration and Anti-Aging - Dr Silvana and Noah Laith
    Nov 6 2024

    Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland

    Timestamps:

    • 00:00 Intro
    • 01:30 What are peptides and how are they made
    • 07:20 Safety of peptides
    • 12:52 FDA and peptides
    • 18:45 BPC157
    • 31:10 TB500
    • 37:20 Growth hormone peptides
    • 44:20 Longevity peptides, Epitalon, Melanotan
    • 52:35 Fundamentals of lifestyle
    • 56:45 Preparing for peptide protocols

    Dr Silvana Laith Instagram: https://www.instagram.com/drsilvanalaith/

    Noah Laith Instagram: https://www.instagram.com/thestoicbiohacker/

    I Took BPC 157 Peptide for 2 Months and Here's What Happened: https://youtu.be/9qc9dhDDDhc

    Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

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    1 hr and 4 mins
  • #425 I Ranked the Best Supplements - 200k Subscriber Livestream
    Nov 3 2024

    Hello, this is a casual livestream. The list is based on my opinion Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

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    51 mins
  • #424 How to Prevent Heart Disease - Dr Paddy Barrett
    Oct 26 2024

    Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland

    Timestamps:

    • 00:00 Intro
    • 00:32 Bon Charge Sponsorship
    • 01:20 Declining Heart Disease Rates
    • 05:10 Biggest Risk Factors of Heart Disease
    • 10:15 What Is Heart Disease and Atherosclerosis
    • 13:55 When Does Atherosclerosis Begin
    • 20:55 Biggest Risk Factors of Heart Disease
    • 27:55 Role of Genetics in Heart Disease
    • 31:50 High vs Low Lipids
    • 39:40 Managing Your Risk Trajectory Over Time
    • 45:30 Lp(a)
    • 52:30 ApoB vs Cholesterol
    • 57:20 Does HDL Reduce the Risk of Heart Disease
    • 59:35 Homocysteine
    • 01:02:55 Does Too Much Exercise Cause Atherosclerosis
    • 01:09:55 Practical Steps to Heart Disease Prevention
    • 01:15:30 Detecting Calcium in the Arteries
    • 01:20:35 Calcified Hard Plaques vs Non-Calcified Plaques
    • 01:22:45 At What Calcium Score Can You Get a Heart Attack

    Dr Paddy Barrett Twitter: https://x.com/paddy_barrett

    Dr Paddy Barrett Substack: https://paddybarrett.substack.com/

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    1 hr and 26 mins
  • #423 Top Longevity Scientist Predicts Dramatic Life Extension by 2035 - Aubrey de Grey
    Oct 17 2024

    Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

    Timestamps:

    • 00:00 Introduction
    • 00:37 Twenty since Aubrey coined the Longevity Escape Velocity
    • 11:13 When will we reach Longevity Escape Velocity
    • 16:45 Slowing down aging vs regeneration
    • 19:44 What breakthroughs we need for longevity escape velocity
    • 24:00 Seven types of aging damage that needs to be repaired
    • 24:37 Loss of cells and stem cells
    • 33:57 Regenerating limbs and organs
    • 36:10 Mitochondrial free radical theory of aging
    • 41:15 Intracellular and Extracellular waste products
    • 47:15 How far is gene therapy now?
    • 49:15 Death resistant cells
    • 53:52 Do you need long telomeres
    • 57:15 Extracellular matrix stiffening and glycation
    • 01:00:48 Biggest breakthroughs in the next 5 years
    • 01:04:30 What to do to live until the longevity escape velocity

    The Longevity Escape Velocity Foundation: https://www.levf.org/

    Aubrey de Grey Twitter: https://x.com/aubreydegrey

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    1 hr and 9 mins
  • #422 Cancer Biologist Shares the Science of Cancer Prevention - Dr Joe Zundell PhD
    Oct 13 2024

    Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

    Timestamps:

    • 00:30 Introduction
    • 00:50 What is cancer
    • 04:30 Does everyone have cancer all the time?
    • 06:30 When does cancer become lethal
    • 11:30 Hallmarks of cancer
    • 21:20 Senescent cells vs cancer cells
    • 25:00 Evolutionary purpose of cancer
    • 27:30 Cancer prevention
    • 30:10 Ultra processed food and cancer risk
    • 35:35 Organic vs non-organic food
    • 38:40 What are carcinogens
    • 45:10 Immune function and cancer
    • 48:15 Meat and cancer
    • 51:20 mTOR and cancer
    • 01:02:20 Glucose, Warburg Effect and cancer
    • 01:07:00 Ketones and cancer
    • 01:11:00 Artificial sweeteners
    • 01:16:40 Environmental toxins

    Dr Joe Zundell YouTube channel: https://www.youtube.com/@dr.joezundell

    Dr Joe Zundell Instagram: https://www.instagram.com/dr.joezundell/

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    1 hr and 26 mins
  • #421 Supplements That HARM Your Heart - Q&A
    Oct 5 2024

    Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland

    Timestamps:

    • 00:01 Supplements that are bad for the heart
    • 08:45 Will we see someone live to 125
    • 11:56 Bon Charge sponsorship
    • 12:46 Maltodextrin in protein powder
    • 13:59 Hyaluronic acid supplementation and cancer
    • 15:32 Creatine reduces VO2 max
    • 17:55 Limiting factor in losing visceral fat
    • 20:45 Which disease am I most afraid of
    • 25:13 Weighted stretching for muscle growth
    • 28:00 Protein restriction and lifespan
    • 32:22 How to train with joint pain
    • 35:39 How much NAC for 60+
    • 37:23 How to stimulate appetite
    • 40:47 What's a good VO2 max for women

    Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

    Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF

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    44 mins
  • #420 The Weird Connection Between Omega 3 and Your Heart Health - Dr William Harris, PhD
    Sep 28 2024

    Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

    Timestamps:

    • 00:37 Omega 3 Health Benefits as of 2024
    • 03:50 Why Are Omega 3 Fats Beneficial
    • 08:57 My New Book The Longevity Leap
    • 09:15 Why Aren't Omega 3s Essential
    • 09:57 What Is the Omega 3 Index
    • 14:45 Is There Risk of Healthy User Bias
    • 17:50 How High Omega 3 Index Is Optimal
    • 26:28 How to Increase Omega 3 Index
    • 29:38 Different Types of Omega 3 Supplements
    • 32:40 Are Omega 3 Supplements Oxidized and Rancid
    • 35:15 How to Choose an Omega 3 Supplement
    • 40:15 Heart Disease and Omega 3s
    • 46:25 Neurodegeneration and Omega 3s
    • 48:00 Omega 6 Fats and Mortality
    • 55:00 How Much Omega 6 Is Too Much
    • 59:48 Omega 9 Fats
    • 01:02:15 How to Store Omega 3 Supplements
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    1 hr and 5 mins